Infection via receptive fellatio (‘doing it’) is biologically plausible and may happen occasionally. However, infection via insertive fellatio (‘having it done to you’) is probably exceedingly low risk. There are no reliable reports of HIV being transmitted from the mouth to the genitals.Ĭases of transmission via cunnilingus are extremely rare, and the reliability of these reports is questionable. How could HIV infect the mouth and throat? There are no reported cases of HIV transmission through kissing. HIV is not able to infect most cells in the mouth. Only one cell type found in the mouth is vulnerable to HIV infection (Campo). The tissue of the mouth and oesophagus is also very thick compared with genital tissues, and fluids stay in contact with it for a very short time because swallowing clears the mouth regularly.